Updated October 2026Expert Reviewed

Advanced Collagen Plus Review 2026Does It Actually Work?

by Advanced Bionutritionals

Rank of Supplements|Medically Reviewed by Editorial Team
Advanced Collagen Plus packaging

Advanced Collagen Plus is an unflavoured collagen powder from Advanced Bionutritionals (Norcross, Georgia), sold for joints, skin, hair and nails. It costs $49.95 a bag, or $41.50 a bag in a 6-pack, with a 90-day money-back guarantee.

Adults who want a multi-source collagen powder
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Score Breakdown

4.2
/ 5
Ingredients
8.4
Dosage
10.0
Value
6.9
Transparency
10.0
Brand
7.0

Pros & Cons

Pros

  • Identifiable US company with a 90-day guarantee on empty bags
  • 11 g of collagen, above trial doses
  • Paid endorsement disclosed

Cons

  • Split between four collagen sources not disclosed
  • Chondroitin 10 mg, under 1% of the studied dose

Who Is This For?

Recommended For:

Adults who want to try a multi-source collagen powder, have no fish or egg allergy, and accept that the skin evidence is weak and the source split is hidden.

Not Recommended For:

People with fish or egg allergies (the blend contains fish collagen and eggshell membrane), anyone due for blood tests without telling their doctor about the biotin, and anyone buying it for the chondroitin.

Summary

What is in it, per 11 g scoop: an 11 g collagen peptide blend from grass-fed beef, eggshell membrane, chicken and fish, plus biotin 2.5 mg and chondroitin sulfate 10 mg. The split between the four sources is not disclosed.

It contains no vitamin C, hyaluronic acid or MSM. An earlier version of this review said it did.

What the evidence says:

  • In trials of specific branded peptides, 2.5 g of collagen a day reduced eye wrinkles, and 5 g eased knee pain during activity.
  • A 2025 meta-analysis found that independent and high-quality trials showed no effect on skin.
  • The 10 mg of chondroitin is under 1% of the dose used in the largest trial, which itself found no benefit over placebo.

Ingredient Breakdown

The label lists, per 11 g scoop: biotin 2.5 mg (8,333% of the daily value); a collagen peptide blend 11 g of hydrolysed grass-fed bovine collagen, eggshell membrane, chicken collagen and hydrolysed fish collagen; and chondroitin sulfate 10 mg. It has 45 calories and no carbohydrate.

The sales page says it provides "5 collagen types from 4 premium sources". The label names the four sources but no collagen types, and gives no test data for them.

What the research shows:

  1. Skin. In 114 women aged 45 to 65, 2.5 g a day of a branded peptide (Verisol) for 8 weeks cut eye-wrinkle volume by 20% vs placebo. But a 2025 meta-analysis of 23 trials found that "studies not receiving funding from pharmaceutical companies revealed no effect". Its conclusion: "There is currently no clinical evidence to support the use of collagen supplements to prevent or treat skin aging."
  2. Joints. In 139 young athletes with knee pain, 5 g a day of specific collagen peptides for 12 weeks eased pain during activity, but not at rest.
  3. Eggshell membrane. 500 mg a day for 8 weeks improved knee pain and stiffness, but not overall scores; the lead author worked for an ingredient company. A 2024 meta-analysis called for better trials.
  4. Chondroitin. The large GAIT trial used 1,200 mg a day and found no benefit over placebo overall.
  5. Biotin. A review found no good evidence for it in healthy people without a deficiency.

What Advanced Collagen Plus does not tell you

No amounts published

Advanced Collagen Plus names its ingredients but publishes no amount for any of them, so there is nothing here to check against the research.

Amounts are taken from the manufacturer’s own supplement facts panel. Where a label states a standardisation, the active fraction is what we compare, because the active is what the trials measured.

Dosage Analysis

Our Dose Check compares the label with the best human studies.

  • Collagen blend: 11 g vs 2.5 g (skin) and 5 g (knee) a day. Above the trial doses, but those trials used specific branded peptides, and this product's split is hidden.
  • Eggshell membrane: undisclosed vs 500 mg a day. Cannot be checked.
  • Chondroitin: 10 mg vs 1,200 mg a day in GAIT. About 0.8%.
  • Biotin: 2.5 mg, far above the daily value, with no benefit shown without a deficiency.

The directions are 1 scoop (11 g) a day, stirred into coffee or another drink. A bag holds 20 servings, so it lasts 20 days, not a month.

Quality & Testing

Our Transparency Score checks five things a buyer can verify. Advanced Collagen Plus scores 2 out of 5.

  • Label with doses: no (partial). Biotin and chondroitin are dosed, but the 11 g blend hides how much comes from each of the four sources.
  • Identifiable company: yes. Advanced Bionutritionals, LLC, 5305 Oakbrook Parkway, Norcross, GA. The endorsing doctor, Frank Shallenberger, is disclosed as paid by the company.
  • Refund terms in writing: yes. 90 days, empty bags accepted, buyer pays return shipping.
  • Independent testing shown: no. The page and label say nothing about manufacturing or testing.
  • Study on the finished product: no.

The FAQ says it is "free of dairy, gluten, and soy", but does not mention fish or egg, both in the blend. On Trustpilot the brand scores 4.3 out of 5 (594 reviews, all products); on PissedConsumer it scores 1.6 out of 5, with complaints about refunds and auto-shipping.

Correction. An earlier version of this review listed vitamin C, hyaluronic acid and MSM, said no amounts were published, stated US manufacture (the product page and label make no such claim), gave a $54 price and said no price was published. We have corrected it.

Value for Money

Prices on the sales page when we checked in September 2026:

  • 1 bag: $49.95.
  • 3 bags: $134.85 ($44.95 each), free shipping.
  • 6 bags: $249.00 ($41.50 each), free shipping.

A bag holds 20 servings, so that is about $2.08 to $2.50 a day. Checkout is handled by Digistore24.

Guarantee. "If you are unsatisfied for any reason, return it within 90 days for a full refund. Even if the bags are empty. You only pay return shipping." We could not open the brand's separate return policy page.

Side Effects & Safety

  • Biotin and lab tests: the FDA warns that biotin can cause falsely low troponin results, a test used to diagnose heart attacks. Tell your doctor you take it before blood tests.
  • Allergens: fish collagen and eggshell membrane are in the blend; the label image shows no allergen statement.

The American Academy of Dermatology says the effectiveness of supplements such as biotin and collagen "is often inconsistent or unreliable". There is no clinical study on Advanced Collagen Plus itself.

Final Verdict

Our Verdict

4.2/5

Advanced Collagen Plus comes from an identifiable company with a 90-day guarantee that covers empty bags. Its 11 g of collagen is above the doses used in trials. But it hides the split between its four sources, adds a token 10 mg of chondroitin, and relies on skin evidence that disappears in independent trials. At 20 servings a bag, it costs $2.08 to $2.50 a day. It is a reasonable collagen powder if you want one, but do not expect proven skin or joint results. Sources: [Proksch et al. 2014, collagen peptides and wrinkles](https://pubmed.ncbi.nlm.nih.gov/24401291/) · [Myung & Park 2025, collagen meta-analysis](https://pubmed.ncbi.nlm.nih.gov/40324552/) · [Zdzieblik et al. 2017, collagen and knee pain](https://pubmed.ncbi.nlm.nih.gov/28177710/) · [Ruff et al. 2009, eggshell membrane](https://pubmed.ncbi.nlm.nih.gov/19340512/) · [Clegg et al. 2006, GAIT trial](https://pubmed.ncbi.nlm.nih.gov/16495392/) · [AAD, supplement myths](https://www.aad.org/news/supplements-debunking-common-myths) · [FDA, biotin and troponin tests](https://www.fda.gov/medical-devices/in-vitro-diagnostics/biotin-interference-troponin-lab-tests-assays-subject-biotin-interference) · Advanced Collagen Plus label and terms, checked 28 September 2026.

Best For:

Adults who want a multi-source collagen powder

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Medical Disclaimer

The content on this page is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult your physician or qualified healthcare provider before starting any new supplement regimen. Individual results may vary.